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The Siggy Blog

Expert articles on medications, conditions, and the future of mental healthcare, from the team building it.

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Featured Conditions & Diagnoses

What Is Major Depressive Disorder? Symptoms, Diagnosis, and Treatment

MDD is more than feeling sad. Here is what the DSM-5 criteria say, how clinicians diagnose it, and which treatments have the strongest evidence.

June 18, 2026Major Depressive DisorderDepression SymptomsDepression Treatment OptionsMood DisordersMDD Diagnosis